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Transforming the understanding and treatment of mental illness through research
DIVISION OF INTRAMURAL RESEARCH PROGRAMS
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 Principal Investigators

Jay Giedd, M.D
Jay Geidd Photo   Dr. Giedd received his M.D. from the University of North Dakota in 1986. He received his training in adult psychiatry at the Menninger Foundation in Topeka, KS, and his Child and Adolescent Psychiatry training at Duke University in Durham, NC. He is board certified in General, Child and Adolescent, and Geriatric Psychiatry. Currently, he is the Chief of the Unit on Brain Imaging in the Child Psychiatry Branch at the NIMH. His research focuses on the biological basis of cognitive, emotional and behavioral disorders.
Research Interests
Dr. Giedd's research team at the Child Psychiatry Branch of the National Institute of Mental Health seeks to use cutting edge technologies to explore the relationship between genes, brain and behavior in healthy development and in neuropsychiatric disorders of childhood onset. They conduct longitudinal neuropsychological and brain imaging studies of healthy twins and singletons as well as clinical groups such as attention-deficit/hyperactivity disorder, childhood-onset schizophrenia, and others. Over the past 10 years they have acquired over 3000 MRI scans making this the largest pediatric neuroimaging project of its kind. The lab also studies sexual dimorphism in the developing brain (especially important in child psychiatry where nearly all disorders have different ages of onsets, prevalence and symptomatology between boys and girls) by exploring clinical populations which have unusual levels of hormones (congenital adrenal hyperplasia, familial precocious puberty) or variations in the sex chromosomes (Klinefelter's syndrome, XYY, XXYY). The lab also conducts studies of monozygotic and dizygotic twins, which are beginning to unravel the relative contributions of genes and environment on a variety of developmental trajectories in the pediatric brain. The group is also involved in the development and application of techniques to analyze brain images and is actively collaborating with other imaging centers throughout the world to advance the image analysis field.
Representative Selected Recent Publications:
  • Giedd JN. Linking adolescent sleep, brain maturation, and behavior. J
    Adolesc Health.
    45(4):319-20. 2009.
  • Johnson SB, Blum RW, Giedd JN. Adolescent maturity and the brain: the
    promise and pitfalls of neuroscience research in adolescent health policy. J
    Adolesc Health
    . 45(3):216-21. 2009.
  • Tiemeier H, Lenroot RK, Greenstein DK, Tran L, Pierson R, Giedd JN.
    Cerebellum development during childhood and adolescence: A longitudinal
    morphometric MRI study. Neuroimage. 2009.
  • Giedd JN, Lalonde FM, Celano MJ, White SL, Wallace GL, Lee NR, Lenroot RK.
    Anatomical brain magnetic resonance imaging of typically developing children
    and adolescents. J Am Acad Child Adolesc Psychiatry. 48(5):465-70. 2009.
  • Shaw P, Wallace GL, Addington A, Evans A, Rapoport J, Giedd JN. Effects of
    the Val158Met catechol-O-methyltransferase polymorphism on cortical
    structure in children and adolescents. Mol Psychiatry. 14(4):348-9. 2009.
  • Lenroot RK, Giedd JN. The changing impact of genes and environment on brain
    development during childhood and adolescence: initial findings from a
    neuroimaging study of pediatric twins. Dev Psychopathol. 20(4):1161-75. 2008.
Address:
Building 10, Room 4C110
10 Center Drive
Bethesda, MD 20892
Phone: 301.435.4517
Email Dr. Giedd
Fax: 301.480.8898
Lab Web Site: http://intramural.nimh.nih.gov/chp/
   
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This page was last updated January 13, 2011.


  The Division of Intramural Research Programs is within the National Institute of Mental Health (NIMH) which is a part of the National Institutes of Health (NIH), a component of the U.S. Department of Health and Human Services.
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