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Transforming the understanding and treatment of mental illness through research DIVISION OF INTRAMURAL RESEARCH PROGRAMS

Staff Scientists and Clinicians Kadharbatcha S. Saleem, Ph.D.   Dr. Saleem attained a B.S and M.S in zoology from Madras University, India. He subsequently received his Ph.D in Neuroanatomy from the same University, where he studied the anatomical organization of cranial nerve nuclei related to eye movements in nocturnal and diurnal primates. Following his thesis work, Dr. Saleem carried out post-doctoral studies in Riken Brain Science Institute, Japan, in the lab of Dr. Keiji Tanaka. During this period he conducted research on the anatomical organization and connections of visual cortical areas and medial temporal lobe memory regions in primates. He also studied the neuronal circuitry in basal ganglia in-vivo using MRI visible contrast agent, in collaboration with Nikos K. Logothetis at the Max-Planck Institute for Biological Cybernetics in Tubingen, Germany. He then moved to the lab of Dr. Joseph L. Price at the Washington University in Saint Louis, where he studied the anatomical interactions of prefrontal cortex with different brain areas in primates. Dr. Saleem moved to the Lab of Neuropsychology/NIMH as a staff scientist in 2009. Research Interests Dr. Saleem has been working on the structural and functional circuitry of the cortex in non-human primates for the past 15 years. He has maintained several collaborations with institutions across different continents (Japan, Germany, and USA) on various projects since 1995. His research has focused on the anatomical networks and connections of orbital, medial and lateral prefrontal cortex with temporal and other cortical areas in macaques. In addition to his collaborations, he recently started his own project in NIMH to study the anatomical organization of processing streams in the auditory and visual cortical areas in primates using two different experimental paradigms; 1) Traditional anatomical track tracing studies using histological and immunohistological methods, and 2) newer track tracing methods using MRI visible contrast agents in live monkeys. A few years ago Dr. Saleem in collaboration with Dr. Nikos Logothetis at the Max-Planck Institute in Germany published a book, "A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates" (2007; Elsevier/Academic Press). This atlas has come to be recognized as the finest atlas of the Rhesus monkey brain because of its exquisite attention to detail and combination with MRI. This atlas is designed to provide an easy to use resource/reference for anatomical, physiological, and functional imaging (fMRI, PET, and MEG) studies in primates. Recently he has published the 2nd edition of this atlas with many updates (see the publication list below). Dr. Saleem also conducted and involved in teaching Human Neuroscience course for Postbac, Postdoc, Ph.D., Premed, and MD students in NIMH (Lab Neuropsychol.), and Washington University in St. Louis. Representative Selected Recent Publications: Saleem KS, Logothetis NK: A combined MRI and histology atlas of the rhesus monkey brain in stereotaxic coordinates. 2nd edition with Horizontal, Coronal and Sagittal series. San Diego: Elsevier/Academic press, 2012. (View PDF) Kravitz D J, Saleem KS, Baker C I, Mishkin M.: A new neural framework for visuospatial processing. Nature Reviews Neuroscience, 12, 217-230. 2011. (View PDF) Saleem KS, Kondo, H, Price JL: Complementary Circuits Connecting the Orbital and Medial Prefrontal Networks with the Temporal, Insular and Opercular Cortex in the Macaque Monkey. J Comp Neurol, 506:659-693. 2008. (View PDF) Saleem KS, Price JL, Hashikawa T: Cytoarchitectonic and chemoarchitectonic subdivisions of the perirhinal and parahippocampal cortex in macaque monkeys. J Comp Neurol, 500 (6):973-1006, 2007. (View PDF) Saleem KS, Pauls J, Augath M, Trinath T, Prause BA, Hashikawa T, Logothetis NK: Magnetic Resonance imaging of neuronal connections in the Macaque Monkey. Neuron, 34: 685-700, 2005. (View PDF) Saleem KS, Suzuki W, Tanaka K, Hashikawa T: Connections between anterior inferotemporal cortex and superior temporal sulcus regions in the macaque monkey. J Neurosci, 20: 5083-5101, 2000. (View PDF) Address: Kadharbatcha Saleem, Ph.D., National Institute of Mental Health (NIMH/NIH) Lab Neuropsychology 49 Convent Drive, Bldg 49, 1B80 MSC 4415 Bethesda, MD 20892 Phone: 301-594-0241 Email Dr. Saleem Fax:   Lab Web Site: http://neuron.nimh.nih.gov/     Principal Investigators Scientists & Clinicians DIRP Labs and Branches DIRP Research Areas Office of the Scientific Director Site Map Participate in Research Contact Us Careers in Research What’s New Functional MRI Core Magnetic Resonance Core Magnetoencephalography Core Microarray Core Neurophysiology Imaging Facility Scientific and Statistical Computing Core Section on Instrumentation Core Transgenic Core Veterinary Medicine Resources (Staff only) Office of the Scientific Director Office of the Clinical Director Office of Fellowship Training Office of Technology Transfer Administrative Services Branch Administrative Services

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The Division of Intramural Research Programs is within the National Institute of Mental Health (NIMH) is a part the National Institutes of Health (NIH), is a component of the U.S. Department of Health and Human Services.