| | Staff Scientists and Clinicians
| Venkata S. Mattay, M.D. |
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Dr. Mattay is the Director of the Neuroimaging Core Facility of the Genes, Cognition and Psychosis Program of the Intramural Research Program, National Institute of Mental Health, National Institutes of Health in Bethesda, Maryland. He attended medical school at Andhra University in India, and did residencies in Neurology at Medical College of Virginia, Virginia Commonwealth University and in Nuclear Medicine at George Washington University. He is board certified in both Neurology and Nuclear Medicine.
Following a two-year fellowship in Functional Neuroimaging with emphasis on Magnetic Resonance Imaging methods in the Laboratory of Diagnostic Radiology Research at the National Institutes of Health, Dr. Mattay joined the Clinical Brain Disorders Branch as a Staff Clinician and clinical imaging scientist.
He has been the recipient of the USPHS Staff Recognition awards in recognition and appreciation of sustained high quality work performance. He is an ad hoc reviewer on several neuroscience and neuroimaging journals and has published over one hundred twenty five scientific articles and authored/coauthored several review articles and chapters.
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| Research Interests |
| Over the last few years, Dr. Mattay and his group have focused their research efforts in studying individual gene effects on brain structure and information processing using MRI methods in normal volunteers across the aging cycle and in patients with neuropsychiatric disorders such as schizophrenia and Parkinson’s disease. His group is also exploring the utility of functional brain imaging in pharmacogenomics by investigating the effects of monoamines on brain circuits subserving higher cognitive function and emotion processing, and variations in genes that affect the neurotransmitters involved in these circuits. |
| Representative Selected Recent Publications: |
- Rasetti R, Sambataro F, Chen Q, Callicott JH, Mattay VS, Weinberger DR.: Altered Cortical Network Dynamics: A Potential Intermediate Phenotype for Schizophrenia and Association With ZNF804A. Arch Gen Psychiatry, 2011.
- Vishnu P. Murty, Fabio Sambataro, Eugenia Radulescu, Mario Altamura, Jennifer Iudicello, Bradley J. Zoltick, Daniel R. Weinberger, Terry E. Goldberg, Venkata S. Mattay.: Updating of working memory content modulates meso-cortico-striatal activity. Neuroimage., Aug 1;57(3):1264-72, 2011.
- Lemaitre H, Goldman AL, Sambataro F, Verchinski BA, Meyer-Lindenberg A, Weinberger DR, Mattay VS.: Normal age-related brain morphometric changes: nonuniformity across cortical thickness, surface area and gray matter volume? Neurobiol Aging., Aug 23. 2010.
- Herve Lemaitre, Venkata Mattay, Fabio Sambataro, Beth Verchinski, Richard Straub, Joseph Callicott, Barbara Lipska, Joel E. Kleinman, Ronald McKay, Daniel R, Weinberger.: Genetic variation in FGF20 modulates hippocampal biology. J Neurosci., Apr 28;30(17):5992-7 2010.
- Roberta Rasetti, Venkata Mattay, Beth Stankevich, Kelsey Skjei, Giuseppe Blasi, Fabio Sambataro, Jose’ A. Apud, Daniel R. Weinberger.: Low dose modafinil dampens amygdala reactivity to salient stimuli while improving efficiency in cognitive information processing. Neuropsychopharmacology., Sep;35(10):2101-9, 2010.
- Fabio Sambataro, Vishnu P. Murty, Herve S. Lemaitre, Jeffrey D. Reed, Saumitra Das, Terry E. Goldberg, Joseph H Callicott, Daniel R. Weinberger, Venkata S. Mattay.: BNDF modulates normal human hippocampal ageing. Molecular Psychiatry, Feb;15(2):116-8, 2010.
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