The mission of the Pediatrics & Developmental Neuropsychiatry Branch (PDN) is to identify factors which influence the onset and expression of psychiatric symptomatology and to develop more effective treatment and prevention strategies for pediatric psychopathology. The Branch currently conducts clinical research on a variety of childhood psychiatric disorders, including obsessive-compulsive disorder, separation anxiety disorder and Tourette’s syndrome. In response to public health concerns about childhood bipolar disorder, and new research opportunities in affective neuroscience, PDN is launching a major new initiative to investigate the phenomenology and treatment of childhood bipolar disorder. These studies will not only provide valuable information about the development of affective stability, but also complement ongoing research of emotional dysregulation in children with PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Strep infections).

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