1. SIMÉON F.G., BROWN A.K., ZOGHBI S.S., PATTERSON V.M., INNIS R.B. & PIKE V.W. Synthesis and simple ¹⁸F-labeling of 3-Fluoro-5-(2-(2-(fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile as a High Affinity Radioligand for Imaging Monkey Brain Metabotropic Glutamate Subtype-5 Receptors with Positron Emission Tomography. J. Med. Chem. (2007) 50, 3256-3266. (Featured in Molecule of the Month; Sharma S. and Lindsley C.W., Curr. Topics in Med. Chem. 2007, 7, 1541-1542). Download PDF

2. RYU Y.H., LIOW J.-S., ZOGHBI S., FUJITA M., COLLINS J., TIPRE J., SANGARE J., HONG J., PIKE V.W. & INNIS R.B. Disulfiram inhibits defluorination of [¹⁸F]FCWAY, reduces bone radioactivity, and enhances visualization of radioligand binding to serotonin 5-HT_1A receptors in human brain. J. Nucl. Med. (2007) 48, 1154-1161. Download PDF

3. SENECA N., CAI L., LIOW J.-S., ZOGHBI S.S., GLADDING R.L., HONG J., PIKE V.W. & INNIS R.B. Brain and whole-body imaging in nonhuman primates with [¹¹C]MeS-IMPY, a candidate radioligand for β-amyloid plaques. Nucl. Med. Biol. (2007) 34, 681-689. Download PDF

4. MCCARRON J.A., ZOGHGBI S.S., SHETTY H.U., VERMEULEN E.S, WIKSTROM H.V., ICHISE M., YASUNO F., HALLDIN C., INNIS R.B. & PIKE V.W. Synthesis and preliminary evaluation of [¹¹C](-)-RWAY in monkey - a new simply labeled antagonist radioligand for imaging brain 5-HT_1A receptors with PET. Eur. J. Nucl. Med. & Mol Imaging (2007) 34, 1670-1682. Download PDF

5. CAI L., CUEVAS J., TEMME S., HERMAN M.M., DAGOSTIN C., WIDDOWSON D.A., INNIS R.B. & PIKE V.W. Synthesis and structure-affinity relationships of new 4-(6-Iodo-H-imidazo[1,2-a]pyridin-2-yl)-N-dimethylbenzeneamine derivatives as ligands for human β-amyloid plaques. J. Med. Chem. (2007) 50, 4746-4758. Download PDF

6. SCHOU M., PIKE V.W. & HALLDIN C. Development of radioligands for imaging of norepinephrine transporters in vivo with positron emission tomography. Current Topics Med. Chem. (2007) 7, 1806-1816. Download PDF

7. BROWN A.K., FUJITA, M., FUJIMURA Y., LIOW J.-S., STABIN M., RYU Y.H., IMAIZUMI M., HONG J., PIKE V.W. & INNIS R.B. Radiation dosimetry and biodistribution in monkey and man of ¹¹C-PBR28, a PET radioligand to image inflammation. J. Nucl. Med. (2007) 48, 2072-2079. Download PDF

8. IMAIZUMO M., BRIARD E., ZOGHBI S.S., GOURLEY J.P., HONG J., MUSACHIO J.L., GLADDING R., PIKE V.W., INNIS R.B. & FUJITA M. Kinetic evaluation in nonhuman primates of two new PET ligands for peripheral benzodiazepine receptors in brain. Synapse (2007) 61, 595-605. Download PDF

9. SHETTY H.U., ZOGHBI S.S., LIOW J.-S., ICHISE M., HONG J.S., MUSACHIO J.L., HALLDIN C., SEIDEL J., INNIS R.B & PIKE V.W. Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand, [¹¹C]PE2I. Eur. J. Nucl. Med. & Mol. Imaging (2007) 34, 667-678. Download PDF

10. RODRIGUEZ-GOMEZ J.A., LU J.-Q., VELASCO I., RIVERA S., ZOGHBI S.S., LIOW J.-S., MUSACHIO J.L., CHIN F.T., TOYAMA H., SEIDEL J., GREEN M.V., THANOS P.K., ICHISE M., PIKE V.W., INNIS R.B. & MCKAY R.D.G. Persistent function of neurons derived from embryonic stem cells in a rodent model of Parkinson disease. Stem Cells (2007) 25, 918-928. Download PDF

11. ZHANG X.-Y, YASUNO F., ZOGHBI S.S., LIOW J-S., HONG J., MCCARRON J.A., PIKE V.W. & INNIS R.B. Quantification of serotonin 5-HT_1A receptors in humans with [¹¹C](R)–(–)–RWAY: radiometabolite(s) likely confound brain measurements. Synapse (2007) 61, 469-477. Download PDF

12. YASUNO F., SANABRIA S.M., BURNS H.D., HARGREAVES R.J., GHOSE S., ICHISE M., CHIN F.T., MORSE C.L., PIKE V.W. & INNIS R.B. PET imaging of neurokinin-1 (NK1) receptors with [¹⁸F]SPA-RQ in human subjects: assessment of reference tissue models and their test-retest reproducibility. Synapse (2007) 61, 242-251. Download PDF

13. FUJITA M., IMAIZUMI M., D'SA C., ZOGHBI S.S., CRESCENZO M.S., HONG J., MUSACHIO J .L., GEE A.D., SEIDEL J., GREEN M.V., PIKE V.W., DUMAN R.S. & INNIS R.B. In vivo and in vitro measurement of brain phosphodiesterase 4 in rats after antidepressant administration. Synapse (2007) 61, 78-86. Download PDF

14. LU S.Y., CLEMENTS J.T., GILDE M.J., PRAK A., WATTS P. & PIKE V.W. Separation of [¹⁸F]fluoride ion from proton-irradiated [¹⁸O]water within an EOF-driven micro-reactor powered by the CapiliX Capella™ platform, J. Label. Compd. Radiopharm., (2007) 50, 597-599. Download PDF

15. LAZAROVA N., SIMEON F.G., MUSACHIO J.L., LU S.Y. & PIKE V.W. Integration of a Microwave Reactor with Synthia to Provide a Fully Automated Radiofluorination Module, J. Label. Compd. Radiopharm., (2007) 50, 463-465. Download PDF

16. CAI, L., INNIS R.B. & PIKE V.W. Radioligand development for PET Imaging of β-amyloid (Aβ) – Current Status. Curr. Med. Chem. (2007) 14, 19-52. Download PDF

17. IMAIZUMI M., KIM H.-J., ZOGHBI S.S., BRIARD E., HONG J., MUSACHIO J.L, RUETZLER C., CHUANG D.-M., PIKE V.W., INNIS R.B. & FUJITA M. PET Imaging with [¹¹C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat. Neurosci. Lett. (2007) 411, 200-205. Download PDF

18. SCHOU M., PIKE V.W., SÓVÁGÁ J., GULYÁS B., GALLAGHER P.T., DOBSON D.R, WALTER M.W., RUDYK H., FARDE L. & HALLDIN C. Synthesis of ¹¹C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET. Bioorg. Med. Chem. (2007) 15, 616-625. Download PDF

19. LIOW J-S., LU S., MCCARRON J.A., HONG J., MUSACHIO J.L., PIKE V.W., INNIS R.B. & ZOGHBI S.S. Effect of a P glycoprotein inhibitor, Cyclosporin A, on the disposition in rodent brain and blood of the 5-HT_1A receptor radioligand, [¹¹C](R)-(?)-RWAY. Synapse (2007) 61, 96-105. Download PDF

20. SPRAGUE D.R., CHIN F.T., LIOW J.-S., FUJITA M., BURNS H.D., HARGREAVES R., STUBBS J.B., PIKE V.W., INNIS R.B. & MOZLEY P.D. Human biodistribution and radiation dosimetry of the tachykinin NK1 antagonist radioligand [¹⁸F]SPA-RQ: comparison of thin-slice, bisected, and 2-D planar image analysis. J. Nucl. Med. (2007) 48, 100-107. Download PDF