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LCS research studies of OCD & related disorders
Genetic and Family Study of OCD and related conditions
We are studying the association of gene variants that affect central neurotransmission in anxiety and negative emotional states along with related psychological conditions. Our preliminary work has shown an association between a genetic variant in the serotonin transporter promoter region and OCD. Additional candidate genes of potential interest are being identified in ongoing studies of OCD and other disorders related to anxiety. We are also participating in a nation-wide genome scan study of OCD.
Participant Information for Genetics & Family Study:
We have previously invited individuals with OCD and their close relatives to participate in our family genetics study. Our current sample at the NIMH, comprising more than 1000 individuals, is being studied as part of collaborations with Johns Hopkins and other universities. This study is no longer admitting new patient volunteers.
All information obtained will remain completely confidential.
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