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Active LCS research studies of OCD & related disorders
1. Genetic and Family Study of OCD and related conditions
2. OCD Neuroimaging Study
All potential participants in the following studies are given an initial evaluation and consultation regarding OCD and related spectrum disorders. This screening process allows you to better understand your condition while providing us with important information regarding your eligibility for our studies.
1. Genetic and Family Study of OCD and related conditions
We are studying the association of gene variants that affect central neurotransmission in anxiety and negative emotional states along with related psychological conditions. Our preliminary work has shown an association between a genetic variant in the serotonin transporter promoter region and OCD. Additional candidate genes of potential interest are being identified in ongoing studies of OCD and other disorders related to anxiety. We are also participating in a nation-wide genome scan study of OCD.
Participant Information for Genetics & Family Study:
We are currently inviting individuals with OCD and their close relatives to participate in our family genetics study. Our current sample at the NIMH, comprising more than 200 individuals, is being enlarged as part of collaborations with Johns Hopkins and other universities. Participants will be asked to:
-complete questionnaires
-participate in a telephone or in-person interview
-provide a sample of blood at no cost to you.
Participants are paid for their time.
All information obtained will remain completely confidential.
For more details or to indicate interest in participating, please refer to our Genetics study protocol or contact Diane Kazuba at (301) 594-0579 or kazubad@mail.nih.gov.
2. OCD Neuroimaging Study
Future study. Please check back periodically for updates.
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