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OCD and human genetics

Murphy DL, Moya PR, Wendland JR, Timpano K. Genetic contributions to obsessive-compulsive disorders (OCD) and OCD-related disorders. Chapter for Principles of Psychiatric Genetics. Editors: John I. Nurnberger Jr. and Wade Berrettini, Cambridge University Press, New York, Chapter 11, 121-133, 2012.

Stewart SE, et al. Genome-wide association study of obsessive-compulsive disorder. Mol Psychiatry, 2012 [Epub ahead of print].

Timpano KR, Rubenstein LM, Murphy DL. Phenomenological features and clinical impact of affective disorders in OCD: a focus on the bipolar disorder and OCD connection. Depression and Anxiety 29:226-33, 2012.

Murphy DL, Moya PR. Human serotonin transporter gene (SLC6A4) variants: their contributions to understanding pharmacogenomic and other functional GxG and GxE differences in health and disease. Curr Opin Pharmacol 11:3-10, 2011.

Nestadt G, et al. Homeobox genes in obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet 159B:53-60, 2012.

Timpano KR, Schmidt NB, Wheaton MG, Wendland JR, Murphy DL. Consideration of the BDNF gene in relation to two phenotypes: Hoarding and obesity. J Abnorm Psychol 120:700-7, 2011.

Murphy DL, Timpano KR, Wheaton MG, Greenberg BD, Miguel EC. Obsessive-compulsive disorder and its related disorders: a reappraisal of obsessive-compulsive spectrum concepts. Dialogues Clin Neurosci 12:131-48, 2010.

Voyiaziakis E, et al. Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study. Mol Psychiatry 16:108-20, 2011.

Wang Y, et al. A screen of SLC1A1 for OCD-related alleles. Am J Med Genet B Neuropsychiatr Genet 153B:675-9, 2010.

Wendland JR, Moya PR, Timpano KR, Anavitarte AP, Kruse MR, Wheaton MG, Ren-Patterson RF, Murphy DL. A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder. Arch Gen Psychiatry 66:408-16, 2009.

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