Selected Student Publications Ahlqvist, J., Donati, D., Martinelli, E., Akhyani, N., Hou, J., Major, E.O., Jacobson, S. & Fogdell-Hahn, A. (2006) Complete replication cycle and acquisition of tegument in nucleus of human herpesvirus 6A in astrocytes and in T-cells. J Med Virol, 78, 1542-1553. [PDF]. Ahlqvist, J., Fotheringham, J., Akhyani, N., Yao, K., Fogdell-Hahn, A. & Jacobson, S. (2005) Differential tropism of human herpesvirus 6 (HHV-6) variants and induction of latency by HHV-6A in oligodendrocytes. J Neurovirol, 11, 384-394. [PDF] Arlinde, C., Sommer, W., Bjork, K., Reimers, M., Hyytia, P., Kiianmaa, K. & Heilig, M. (2004) A cluster of differentially expressed signal transduction genes identified by microarray analysis in a rat genetic model of alcoholism. Pharmacogenomics J, 4, 208-218. [PDF] Bjork, K., Rimondini, R., Hansson, A.C., Terasmaa, A., Hyytia, P., Heilig, M. & Sommer, W.H. (2008) Modulation of voluntary ethanol consumption by beta-arrestin 2. Faseb J, 22, 2552-2560. [PDF] Bjork, K., Saarikoski, S.T., Arlinde, C., Kovanen, L., Osei-Hyiaman, D., Ubaldi, M., Reimers, M., Hyytia, P., Heilig, M. & Sommer, W.H. (2006) Glutathione-S-transferase expression in the brain: possible role in ethanol preference and longevity. Faseb J, 20, 1826-1835. [PDF] Blackinton, J., Ahmad, R., Miller, D.W., van der Brug, M.P., Canet-Aviles, R.M., Hague, S.M., Kaleem, M. & Cookson, M.R. (2005) Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization. Brain Res Mol Brain Res., 134, 76-83. [PDF] Blackinton, J., Kumaran, R., van der Brug, M.P., Ahmad, R., Olson, L., Galter, D., Lees, A., Bandopadhyay, R. & Cookson, M.R. (2009a) Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease. Neurosci Lett, 452, 8-11. [PDF] Blackinton, J., Lakshminarasimhan, M., Thomas, K.J., Ahmad, R., Greggio, E., Raza, A.S., Cookson, M.R. & Wilson, M.A. (2009b) Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1. J Biol Chem, 284, 6476-6485. [PDF] Blackinton, J.G., Anvret, A., Beilina, A., Olson, L., Cookson, M.R. & Galter, D. (2007) Expression of PINK1 mRNA in human and rodent brain and in Parkinson's disease. Brain Res, 1184, 10-16. [PDF] Bryceson, Y.T., March, M.E., Barber, D.F., Ljunggren, H.G. & Long, E.O. (2005) Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells. J Exp Med., 202, 1001-1012. [PDF] Bryceson, Y.T., March, M.E., Ljunggren, H.G., Long, E.O., 2006. Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood. 107, 159-66. [PDF] Bryceson, Y.T., Rudd, E., Zheng, C., Edner, J., Ma, D., Wood, S.M., Bechensteen, A.G., Boelens, J.J., Celkan, T., Farah, R.A., Hultenby, K., Winiarski, J., Roche, P.A., Nordenskjold, M., Henter, J.I., Long, E.O., Ljunggren, H.G., 2007. Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients. Blood. 110, 1906-15. [PDF] Carrasquillo, M.M., Nicholson, A.M., Finch, N., Gibbs, J.R., Baker, M., Rutherford, N.J., Hunter, T.A., DeJesus-Hernandez, M., Bisceglio, G.D., Mackenzie, I.R., Singleton, A., Cookson, M.R., Crook, J.E., Dillman, A., Hernandez, D., Petersen, R.C., Graff-Radford, N.R., Younkin, S.G., Rademakers, R., 2010. Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma. Am J Hum Genet. 87, 890-7. [PDF] Culp, W.D., Neal, R., Massey, R., Egevad, L., Pisa, P., Garland, D., 2006. Proteomic analysis of tumor establishment and growth in the B16-F10 mouse melanoma model. J Proteome Res. 5, 1332-43. [PDF] Culp, W.D., Tsagozis, P., Burgio, M., Russell, P., Pisa, P., Garland, D., 2007. Interference of macrophage migration inhibitory factor expression in a mouse melanoma inhibits tumor establishment by up-regulating thrombospondin-1. Mol Cancer Res. 5, 1225-31. [PDF] Dehvari, N., Sandebring, A., Flores-Morales, A., Mateos, L., Chuan, Y.C., Goldberg, M.S., Cookson, M.R., Cowburn, R.F., Cedazo-Minguez, A., 2009. Parkin-mediated ubiquitination regulates phospholipase C-gamma1. J Cell Mol Med. 13, 3061-8. [PDF] Donati, D., Martinelli, E., Cassiani-Ingoni, R., Ahlqvist, J., Hou, J., Major, E.O., Jacobson, S., 2005. Variant-specific tropism of human herpesvirus 6 in human astrocytes. J Virol. 79, 9439-48. [PDF] Donohue, S.R., Halldin, C., Pike, V.W., 2006. Synthesis and structure-activity relationships (SARs) of 1,5-diarylpyrazole cannabinoid type-1 (CB(1)) receptor ligands for potential use in molecular imaging. Bioorg Med Chem Lett. 14, 3712-20. [PDF] Donohue, S.R., Halldin, C., Pike, V.W., 2008a. A facile and regioselective synthesis of rimonabant through an enamine-directed 1,3-dipolar cycloaddition. Tetrahedron Lett. 49, 2789-2791. [PDF] Donohue, S.R., Halldin, C., Schou, M., Hong, J., Phebus, L., Chernet, E., Hitchcock, S.A., Gardinier, K.M., Ruley, K.M., Krushinski, J.H., Schaus, J.M., Pike, V.W., 2008b. Radiolabeling of a high potency cannabinoid subtype-1 receptor ligand, N-(4-fluoro-benzyl)-4-(3-(piperidin-1-yl)-indole-1- sulfonyl)benzamide (PipISB), with carbon-11 or fluorine-18. J Label Compd Radiopharm. 51, 146-152. [PDF] Donohue, S.R., Krushinski, J.H., Pike, V.W., Chernet, E., Phebus, L., Chesterfield, A.K., Felder, C.C., Halldin, C., Schaus, J.M., 2008c. Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging. J Med Chem. 51, 5833-42. [PDF] Donohue, S.R., Pike, V.W., Finnema, S.J., Truong, P., Andersson, J., Gulyas, B., Halldin, C., 2008d. Discovery and labeling of high-affinity 3,4-diarylpyrazolines as candidate radioligands for in vivo imaging of cannabinoid subtype-1 (CB1) receptors. J Med Chem. 51, 5608-16. [PDF] Donohue, S.R., Zoghbi, S.S., Yasuno, F., Gourley, J.P., Innis, R.B., Halldin, C., Pike, V.W., 2008e. Radiosynthesis and evaluation in monkey of three 11C-labelled 1,5-diarylpyrazoles as high potency candidate PET radioligands for cannabinoid subtype-1(CB1)receptors in brain. Curr Radiopharmaceuticals. 1, 93-102. [PDF] Eriksson, F., Culp, W.D., Massey, R., Egevad, L., Garland, D., Persson, M.A., Pisa, P., 2007. Tumor specific phage particles promote tumor regression in a mouse melanoma model. Cancer Immunol Immunother. 56, 677-87. [PDF] Evergren, E., Gad, H., Walther, K., Sundborger, A., Tomilin, N., Shupliakov, O., 2007. Intersectin is a negative regulator of dynamin recruitment to the synaptic endocytic zone in the central synapse. J Neurosci. 27, 379-90. [PDF] Finnema, S.J., Donohue, S.R., Zoghbi, S.S., Brown, A.K., Gulyas, B., Innis, R.B., Halldin, C., Pike, V.W., 2009. Evaluation of [11C]PipISB and [18F]PipISB in monkey as candidate radioligands for imaging brain cannabinoid type-1 receptors in vivo. Synapse. 63, 22-30. [PDF] Freed, W.J., Chen, J., Backman, C.M., Schwartz, C.M., Vazin, T., Cai, J., Spivak, C.E., Lupica, C.R., Rao, M.S., Zeng, X., 2008. Gene expression profile of neuronal progenitor cells derived from hESCs: activation of chromosome 11p15.5 and comparison to human dopaminergic neurons. PLoS One. 3, e1422. [PDF] Hammarstedt, M., Ahlqvist, J., Jacobson, S., Garoff, H., Fogdell-Hahn, A., 2007. Purification of infectious human herpesvirus 6A virions and association of host cell proteins. Virol J. 4, 101. [PDF] Hansson, A.C., Cippitelli, A., Sommer, W.H., Fedeli, A., Bjork, K., Soverchia, L., Terasmaa, A., Massi, M., Heilig, M., Ciccocioppo, R., 2006. Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress. Proc Natl Acad Sci U S A. 103, 15236-41. [PDF] Henriksson, R., Kuzmin, A., Okvist, A., Harper, C., Sheedy, D., Garrick, T., Yakovleva, T., Bakalkin, G., 2008. Elevated synaptophysin I in the prefrontal cortex of human chronic alcoholics. Synapse. 62, 829-33. [PDF] Jacob, S., Johansson, C., Ulfendahl, M., Fridberger, A., 2009. A digital heterodyne laser interferometer for studying cochlear mechanics. J Neurosci Methods. 179, 271-7. [PDF] Kannan, P., Brimacombe, K.R., Kreisl, W.C., Liow, J.S., Zoghbi, S.S., Telu, S., Zhang, Y., Pike, V.W., Halldin, C., Gottesman, M.M., Innis, R.B., Hall, M.D., 2010. Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PET. Proc Natl Acad Sci U S A. 108, 2593-8. Epub 2011 Jan 24. [PDF] Kannan, P., Brimacombe, K.R., Zoghbi, S.S., Liow, J.S., Morse, C., Taku, A.K., Pike, V.W., Halldin, C., Innis, R.B., Gottesman, M.M., Hall, M.D., 2011. N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrier. Drug Metab Dispos. 38, 917-22. [PDF] Karabanov, A., Blom, O., Forsman, L., Ullen, F., 2009. The dorsal auditory pathway is involved in performance of both visual and auditory rhythms. Neuroimage. 44, 480-8. [PDF] Karabanov, A., Cervenka, S., de Manzano, O., Forssberg, H., Farde, L., Ullen, F., 2010. Dopamine D2 receptor density in the limbic striatum is related to implicit but not explicit movement sequence learning. Proc Natl Acad Sci U S A. 107, 7574-9. [PDF] Karlsson, R.M., Holmes, A., Heilig, M., Crawley, J.N., 2005. Anxiolytic-like actions of centrally-administered neuropeptide Y, but not galanin, in C57BL/6J mice. Pharmacol Biochem Behav. 80, 427-36. [PDF] Karlsson, R.M., Choe, J.S., Cameron, H.A., Thorsell, A., Crawley, J.N., Holmes, A., Heilig, M., 2008a. The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice. Psychopharmacology (Berl). 195, 547-57. [PDF] Karlsson, R.M., Tanaka, K., Heilig, M., Holmes, A., 2008b. Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist. Biol Psychiatry. 64, 810-4. [PDF] Karlsson, R.M., Tanaka, K., Saksida, L.M., Bussey, T.J., Heilig, M., Holmes, A., 2009. Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia. Neuropsychopharmacology. 34, 1578-89. [PDF] Kilander, M.B., Dijksterhuis, J.P., Ganji, R.S., Bryja, V., Schulte, G., 2011. WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins. Cell Signal. 23, 550-4. [PDF] Kiselycznyk, C., Holmes, A., 2011. All (C57BL/6) Mice are not Created Equal. Front Neurosci. 5, 10. [PDF] Kiselycznyk, C.L., Svenningsson, P., Delpire, E., Holmes, A., 2011. Genetic, pharmacological and lesion analyses reveal a selective role for corticohippocampal GLUN2B in a novel repeated swim stress paradigm. Neuroscience. June 22 [Epub ahead of print]. [PDF] Klaus, A., Planert, H., Hjorth, J., Berke, J.D., Silberberg, G., and Hellgren Kotaleski, J., 2011. Striatal fast-spiking interneurons: from firing patterns to postsynaptic impact. Front Syst Neurosci. 5, July 13 [Epub ahead of print]. [PDF] Klaus, A., Yu, S., Plenz, D., 2011. Statistical analyses support power law distributions found in neuronal avalanches. PLoS. 6, e19779. [PDF] Klaus, A., Warrant, E.J., 2009. Optimum spatiotemporal receptive fields for vision in dim light. J Vis. 9, 18.1-16. [PDF] Lindstrom, K.M., Guyer, A.E., Mogg, K., Bradley, B.P., Fox, N.A., Ernst, M., Nelson, E.E., Leibenluft, E., Britton, J.C., Monk, C.S., Pine, D.S., Bar-Haim, Y., 2009. Normative data on development of neural and behavioral mechanisms underlying attention orienting toward social-emotional stimuli: an exploratory study. Brain Res. 1292, 61-70. [PDF] Lindstrom, K.M., Mandell, D.J., Musa, G.J., Britton, J.C., Sankin, L.S., Mogg, K., Bradley, B.P., Ernst, M., Doan, T., Bar-Haim, Y., Leibenluft, E., Pine, D.S., Hoven, C.W., 2011. Attention orientation in parents exposed to the 9/11 terrorist attacks and their children. Psychiatry Res. 187, 261-6. [PDF] Lundstrom, W., Greiner, E., Lundmark, F., Westerlind, H., Smestad, C., Lorentzen, A.R., Kockum, I., Link, J., Brynedal, B., Celius, E.G., Harbo, H.F., Masterman, T., Hillert, J., 2011. No influence on disease progression of non-HLA susceptibility genes in MS. J Neuroimmunol. July 8 [Epub ahead of print]. [PDF] Luo, Y., Schwartz, C., Shin, S., Zeng, X., Chen, N., Wang, Y., Yu, X., Rao, M.S., 2006. A focused microarray to assess dopaminergic and glial cell differentiation from fetal tissue or embryonic stem cells. Stem Cells. 24, 865-75. [PDF] Mailliet, F., Qi, H., Rocher, C., Spedding, M., Svenningsson, P., Jay, T.M., 2008. Protection of stress-induced impairment of hippocampal/prefrontal LTP through blockade of glucocorticoid receptors: implication of MEK signaling. Exp Neurol. 211, 593-6. [PDF] Marks, C.A., Cheng, K., Cummings, D.M., Belluscio, L., 2006. Activity-dependent plasticity in the olfactory intrabulbar map. J Neurosci. 26, 11257-66. [PDF] Meijer, I.A., Dion, P., Laurent, S., Dupre, N., Brais, B., Levert, A., Puymirat, J., Rioux, M.F., Sylvain, M., Zhu, P.P., Soderblom, C., Stadler, J., Blackstone, C., Rouleau, G.A., 2007. Characterization of a novel SPG3A deletion in a French-Canadian family. Ann Neurol. 61, 599-603. [PDF] Nguyen, M.Q., Marks, C.A., Belluscio, L., Ryba, N.J., 2010. Early expression of odorant receptors distorts the olfactory circuitry. J Neurosci. 30, 9271-9. [PDF] Pechstein, A., Bacetic, J., Vahedi-Faridi, A., Gromova, K., Sundborger, A., Tomlin, N., Krainer, G., Vorontsova, O., Schafer, J.G., Owe, S.G., Cousin, M.A., Saenger, W., Shupliakov, O., Haucke, V., 2010. Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2. Proc Natl Acad Sci U S A. 107, 4206-11. [PDF] Petkova, V.I., Bjornsdotter, M., Gentile, G., Jonsson, T., Li, T.Q., Ehrsson, H.H., 2011a. From part- to whole-body ownership in the multisensory brain. Curr Biol. 21, 1118-22. [PDF] Petkova, V.I., Khoshnevis, M., Ehrsson, H.H., 2011b. The perspective matters! Multisensory integration in ego-centric reference frames determines full-body ownership. Front Psychol. 2 [Epub ahead of print]. [PDF] Plenz, D., Stewart, C. V., Shew, W., Yang, H., Klaus, A., Bellay, T., 2011. Multi-electrode array recordings of neuronal avalanches in organotypic cultures. J Vis Exp. 54. pii: 2949. doi: 10.3791/2949. [PDF] Qi, H., Mailliet, F., Spedding, M., Rocher, C., Zhang, X., Delagrange, P., McEwen, B., Jay, T.M., Svenningsson, P., 2009. Antidepressants reverse the attenuation of the neurotrophic MEK/MAPK cascade in frontal cortex by elevated platform stress; reversal of effects on LTP is associated with GluA1 phosphorylation. Neuropharmacology. 56, 37-46. Epub 2008 Jul 9. [PDF] Rajagopalan, S., Bryceson, Y.T., Kuppusamy, S.P., Geraghty, D.E., van der Meer, A., Joosten, I., Long, E.O., 2006. Activation of NK cells by an endocytosed receptor for soluble HLA-G. PLoS Biol. 4, e9. [PDF] Rao, Y., Ma, Q., Vahedi-Faridi, A., Sundborger, A., Pechstein, A., Puchkov, D., Luo, L., Shupliakov, O., Saenger, W., Haucke, V., 2010. Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation. Proc Natl Acad Sci U S A. 107, 8213-8. [PDF] Rismanchi, N., Soderblom, C., Stadler, J., Zhu, P.P., Blackstone, C., 2008. Atlastin GTPases are required for Golgi apparatus and ER morphogenesis. Hum Mol Genet. 17, 1591-604. [PDF] Rudd, E., Bryceson, Y.T., Zheng, C., Edner, J., Wood, S.M., Ramme, K., Gavhed, S., Gurgey, A., Hellebostad, M., Bechensteen, A.G., Ljunggren, H.G., Fadeel, B., Nordenskjold, M., Henter, J.I., 2008. Spectrum, and clinical and functional implications of UNC13D mutations in familial haemophagocytic lymphohistiocytosis. J Med Genet. 45, 134-41. [PDF] Sandebring, A., Dehvari, N., Perez-Manso, M., Thomas, K.J., Karpilovski, E., Cookson, M.R., Cowburn, R.F., Cedazo-Minguez, A., 2009a. Parkin deficiency disrupts calcium homeostasis by modulating phospholipase C signalling. Febs J. 276, 5041-52. [PDF] Sandebring, A., Thomas, K.J., Beilina, A., van der Brug, M., Cleland, M.M., Ahmad, R., Miller, D.W., Zambrano, I., Cowburn, R.F., Behbahani, H., Cedazo-Minguez, A., Cookson, M.R., 2009b. Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1. PLoS One. 4, e5701. [PDF] Schou, M., Halldin, C., Sovago, J., Pike, V.W., Gulyas, B., Mozley, P.D., Johnson, D.P., Hall, H., Innis, R.B., Farde, L., 2003. Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand, (S,S)-[11C]MeNER. Nucl Med Biol. 30, 707-14. [PDF] Schou, M., Halldin, C., Sovago, J., Pike, V.W., Hall, H., Gulyas, B., Mozley, P.D., Dobson, D., Shchukin, E., Innis, R.B., Farde, L., 2004. PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain. Synapse. 53, 57-67. [PDF] Schou, M., Halldin, C., Pike, V.W., Mozley, P.D., Dobson, D., Innis, R.B., Farde, L., Hall, H., 2005. Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2. Eur Neuropsychopharmacol. 15, 517-20. [PDF] Schou, M., Sovago, J., Pike, V.W., Gulyas, B., Bogeso, K.P., Farde, L., Halldin, C., 2006. Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram. Mol Imaging Biol. 8, 1-8. [PDF] Schou, M., Pike, V.W., Sovago, J., Gulyas, B., Gallagher, P.T., Dobson, D.R., Walter, M.W., Rudyk, H., Farde, L., Halldin, C., 2007. Synthesis of 11C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET. Bioorg Med Chem. 15, 616-25. [PDF] Schou, M., Zoghbi, S.S., Shetty, H.U., Shchukin, E., Liow, J.S., Hong, J., Andree, B.A., Gulyas, B., Farde, L., Innis, R.B., Pike, V.W., Halldin, C., 2009. Investigation of the metabolites of (S,S)-[(11)C]MeNER in humans, monkeys and rats. Mol Imaging Biol. 11, 23-30. [PDF] Schwartz, C.M., Spivak, C.E., Baker, S.C., McDaniel, T.K., Loring, J.F., Nguyen, C., Chrest, F.J., Wersto, R., Arenas, E., Zeng, X., Freed, W.J., Rao, M.S., 2005. NTera2: a model system to study dopaminergic differentiation of human embryonic stem cells. Stem Cells Dev. 14, 517-34. [PDF] Seneca, N., Andree, B., Sjoholm, N., Schou, M., Pauli, S., Mozley, P.D., Stubbs, J.B., Liow, J.S., Sovago, J., Gulyas, B., Innis, R., Halldin, C., 2005. Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates. Nucl Med Commun. 26, 695-700. [PDF] Seneca, N., Finnema, S.J., Farde, L., Gulyas, B., Wikstrom, H.V., Halldin, C., Innis, R.B., 2006a. Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride. Synapse. 59, 260-9. [PDF] Seneca, N., Gulyas, B., Varrone, A., Schou, M., Airaksinen, A., Tauscher, J., Vandenhende, F., Kielbasa, W., Farde, L., Innis, R.B., Halldin, C., 2006b. Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2. Psychopharmacology (Berl). 188, 119-27. [PDF] Seneca, N., Skinbjerg, M., Zoghbi, S.S., Liow, J.S., Gladding, R.L., Hong, J., Kannan, P., Tuan, E., Sibley, D.R., Halldin, C., Pike, V.W., Innis, R.B., 2008a. Kinetic brain analysis and whole-body imaging in monkey of [11C]MNPA: a dopamine agonist radioligand. Synapse. 62, 700-9. [PDF] Seneca, N., Zoghbi, S.S., Skinbjerg, M., Liow, J.S., Hong, J., Sibley, D.R., Pike, V.W., Halldin, C., Innis, R.B., 2008b. Occupancy of dopamine D2/3 receptors in rat brain by endogenous dopamine measured with the agonist positron emission tomography radioligand [11C]MNPA. Synapse. 62, 756-63. [PDF] Seneca, N., Finnema, S.J., Laszlovszky, I., Kiss, B., Horvath, A., Pasztor, G., Kapas, M., Gyertyan, I., Farkas, S., Innis, R.B., Halldin, C., Gulyas, B., 2011. Occupancy of dopamine D(2) and D (3) and serotonin 5-HT (1A) receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography. Psychopharmacology. May 28 [Epub ahead of print]. [PDF] Skinbjerg, M., Ariano, M.A., Thorsell, A., Heilig, M., Halldin, C., Innis, R.B., Sibley, D.R., 2009a. Arrestin3 mediates D(2) dopamine receptor internalization. Synapse. 63, 621-4. [PDF] Skinbjerg, M., Namkung, Y., Halldin, C., Innis, R.B., Sibley, D.R., 2009b. Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors. Synapse. 63, 462-75. [PDF] Skinbjerg, M., Liow, J.S., Seneca, N., Hong, J., Lu, S., Thorsell, A., Heilig, M., Pike, V.W., Halldin, C., Sibley, D.R., Innis, R.B., 2010a. D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model. Neuroimage. 50, 1402-1407. [PDF] Skinbjerg, M., Seneca, N., Liow, J.S., Hong, J., Weinshenker, D., Pike, V.W., Halldin, C., Sibley, D.R., Innis, R.B., 2010b. Dopamine beta-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding. Synapse. 64, 699-703. [PDF] Soderblom, C., Stadler, J., Jupille, H., Blackstone, C., Shupliakov, O., Hanna, M.C., 2010. Targeted disruption of the Mast syndrome gene SPG21 in mice impairs hind limb function and alters axon branching in cultured cortical neurons. Neurogenetics. 11, 369-78. [PDF] Sterky, F.H., Larsson, N.G., 2008. Complex I: a complex gateway to the powerhouse. Cell Metab. 7, 278-9. [PDF] Sterky, F.H., Ruzzenente, B., Gustafsson, C.M., Samuelsson, T., Larsson, N.G., 2010. LRPPRC is a mitochondrial matrix protein that is conserved in metazoans. Biochem Biophys Res Commun. 398, 759-64. [PDF] Sundborger, A., Soderblom, C., Vorontsova, O., Evergren, E., Hinshaw, J.E., Shupliakov, O., 2011. An endophilin-dynamin complex promotes budding of clathrin-coated vesicles during synaptic vesicle recycling. J Cell Sci. 124, 133-43. [PDF] Svenningsson, P., Bateup, H., Qi, H., Takamiya, K., Huganir, R.L., Spedding, M., Roth, B.L., McEwen, B.S., Greengard, P., 2007a. Involvement of AMPA receptor phosphorylation in antidepressant actions with special reference to tianeptine. Eur J Neurosci. 26, 3509-17. [PDF] Svenningsson, P., Tzavara, E.T., Qi, H., Carruthers, R., Witkin, J.M., Nomikos, G.G., Greengard, P., 2007b. Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation. J Neurosci. 27, 4201-9. [PDF] Swanson, C.J., Blackburn, T.P., Zhang, X., Zheng, K., Xu, Z.Q., Hokfelt, T., Wolinsky, T.D., Konkel, M.J., Chen, H., Zhong, H., Walker, M.W., Craig, D.A., Gerald, C.P., Branchek, T.A., 2005. Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc Natl Acad Sci U S A. 102, 17489-94. [PDF] Terry, G., Liow, J.S., Chernet, E., Zoghbi, S.S., Phebus, L., Felder, C.C., Tauscher, J., Schaus, J.M., Pike, V.W., Halldin, C., Innis, R.B., 2008. Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents. Neuroimage. 41, 690-8. [PDF] Terry, G.E., Liow, J.S., Zoghbi, S.S., Hirvonen, J., Farris, A.G., Lerner, A., Tauscher, J.T., Schaus, J.M., Phebus, L., Felder, C.C., Morse, C.L., Hong, J.S., Pike, V.W., Halldin, C., Innis, R.B., 2009. Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand. Neuroimage. 48, 362-70. [PDF] Terry, G.E., Hirvonen, J., Liow, J.S., Seneca, N., Tauscher, J.T., Schaus, J.M., Phebus, L., Felder, C.C., Morse, C.L., Pike, V.W., Halldin, C., Innis, R.B., 2010a. Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB1 receptors using positron emission tomography. Eur J Nucl Med Mol Imaging. 37, 1499-506. [PDF] Terry, G.E., Hirvonen, J., Liow, J.S., Zoghbi, S.S., Gladding, R., Tauscher, J.T., Schaus, J.M., Phebus, L., Felder, C.C., Morse, C.L., Donohue, S.R., Pike, V.W., Halldin, C., Innis, R.B., 2010b. Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands. J Nucl Med. 51, 112-20. [PDF] Thomas, K.J., McCoy, M.K., Blackinton, J., Beilina, A., van der Brug, M., Sandebring, A., Miller, D., Maric, D., Cedazo-Minguez, A., Cookson, M.R., 2011. DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. Hum Mol Genet. 20, 40-50. [PDF] Traynor, B.J., Nalls, M., Lai, S.L., Gibbs, R.J., Schymick, J.C., Arepalli, S., Hernandez, D., van der Brug, M.P., Johnson, J.O., Dillman, A., Cookson, M., Moglia, C., Calvo, A., Restagno, G., Mora, G., Chio, A., 2010. Kinesin-associated protein 3 (KIFAP3) has no effect on survival in a population-based cohort of ALS patients. Proc Natl Acad Sci U S A. 107, 12335-8. [PDF] van der Brug, M.P., Blackinton, J., Chandran, J., Hao, L.Y., Lal, A., Mazan-Mamczarz, K., Martindale, J., Xie, C., Ahmad, R., Thomas, K.J., Beilina, A., Gibbs, J.R., Ding, J., Myers, A.J., Zhan, M., Cai, H., Bonini, N.M., Gorospe, M., Cookson, M.R., 2008. RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proc Natl Acad Sci U S A. 105, 10244-9. [PDF] Watanabe, H., Henriksson, R., Ohnishi, Y.N., Ohnishi, Y.H., Harper, C., Sheedy, D., Garrick, T., Nyberg, F., Nestler, E.J., Bakalkin, G., Yakovleva, T., 2009. FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices of human alcoholics. Addict Biol. 14, 294-7. [PDF] Xia, S., Dun, X.P., Hu, P.S., Kjaer, S., Zheng, K., Qian, Y., Solen, C., Xu, T., Fredholm, B., Hokfelt, T., Xu, Z.Q., 2008. Postendocytotic traffic of the galanin R1 receptor: a lysosomal signal motif on the cytoplasmic terminus. Proc Natl Acad Sci U S A. 105, 5609-13. [PDF] Zhu, P.P., Soderblom, C., Tao-Cheng, J.H., Stadler, J., Blackstone, C., 2006. SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development. Hum Mol Genet. 15, 1343-53. [PDF] |
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