Articles - Selected Publications 2005-2008

Tan HY, Nicodemus KK, Chen Q, Li Z, Brooke JK, Honea R, Kolachana BS, Straub RE, Meyer-Lindenberg A, Sei Y, Mattay VS, Callicott JH and Weinberger DR: Genetic variation in AKT1 is linked to dopaminergic prefrontal cortex structure and function in humans. J Clin Investigation, 118:2200-2208, 2008.(PDF)

Sartorius LJ, Weinberger DR, Hyde TM, Harrison PJ, Kleinman JE and Lipska BK: Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP. Neuropsychopharmacology, 33:2626-2634, 2008. (PDF)

Weickert CS, Miranda-Angulo AL, Wong J, Perlman WR, Ward SE, Vakkalanka R, Straub RE, Weinberger DR and Kleinman JE: Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia. Hum Mol Genet 17:2293-2309, 2008.(PDF)

Meyer-Lindenberg A, Straub RE, Lipska BK, Verchinski BA, Goldberg TE, Callicott JH, Egan MF, Huffaker SS, Mattay VS, Kolachana BS, Kleinman JE, Weinberger DR: Genetic evidence implicating DARPP-32 in human fronto-striatal structure, function and cognition, J. Clin. Investigation 107:672-682, 2007.(PDF)

Law AJ, Kleinman JE, Weinberger DR and Weickert CS: Disease associated intronic variants in the ErBb4 gene are related to altered erbb4 splice variant expression in the brain in schizophrenia. Hum Mol Genet 16:129-144, 2007.(PDF)

Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R, Harrison PJ, Kleinman JE, Weinberger DR: Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the dise. Proc Natl Acad Sci (USA) 103:6747-6752, 2006.(PDF)

Lipska BK, Peters T, Hyde TM, Halim N, Horowitz C, Mitkus S, Weickert CS, Matsumoto M, Sawa A, Straub RE, Vakkalanka R, Herman MM, Weinberger DR and Kleinman JE: Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Hum Mol Gen 15:1245-1258, 2006.(PDF)

Meyer-Lindenberg A, Nichols T, Callicott J, Straub RE, Ding J, Kolachana B, Buckholtz J, Mattay VS, Egan MF and Weinberger DR: Impact of complex genetic variation in COMT on human brain function. Mol Psychiatry 11:867-877, 2006.(PDF)

Pezawas L, Meyer-Lindenberg A, Drabant EM, Verchinski BA, Munoz K, Kolachana BS, Egan MF, Mattay VS and Weinberger DR: 5-HTTLPR polymorphism impacts human cingulated-amygdala interactions: A genetic susceptibility mechanism for depression. Nature Neurosci 8:828-834, 2005.(PDF)